The project
BRAVꓱ at a glance
Computational biomechanics and bioengineering 3D printing to develop a personalised regenerative biological ventricular assist device to provide lasting functional support to damaged hearts.
The BRAVꓱ project aims to develop a regenerative treatment for ischemic heart disease (IHD): an innovative biological ventricular assist device (BioVAD). It is a scaffold that is disposed over the injured area and helps the cardiac cells to make the contraction force needed for an adequate pumping. BRAVꓱ will develop a tailored structure that will be seeded with human induced pluripotent stem cells (hiPSCs), creating cardiac tissue that will be integrated in the patient’s heart.
This approach aims to replace current ventricular assist devices (VADs) to provide temporal functional support to damaged hearts but can’t replace the function of the lost cardiac muscle.
As IHD is the leading single cause of death in the European Union, this approach aims to improve the patient’s quality of life with a single intervention.
The project in numbers
Gender Balance
Impacts
Project structure
General Assembly
FELIPE PROSPER
Universidad de Navarra
JÜRGEN GROLL
University Hospital Würzburg
NURIA MONSERRAT
Fundacio Institut de Bioenginyeria
de Catalunya
MANUEL DOBLARÉ
Universidad de Zaragoza
PETER BOVENDEERD
Technische Universiteit
Eindhoven
Fº FERNANDEZ-AVILÉS
Servicio Madrileño de Salud
PAULA ALVES
Instituto de Biologia
Experimental e Tecnologica
PEDRO MOREO
EBERS Medical Technology
STEFAN JANSSENS
Katholieke Universiteit Leuven
JOS MALDA
Universitair Medisch Centrum Utrecht
ANE M. ZALDÚA
Leartiker
AIDEN FLANAGAN
Boston Scientific
JOHANNES PAULIDES
AE Medicalis
JEANETT BOLTHER
PNO Innovation
Steering Committee
FELIPE PROSPER
Universidad de Navarra
JÜRGEN GROLL
University Hospital Würzburg
NURIA MONSERRAT
Fundacio Institut de Bioenginyeria
de Catalunya
ANE M. ZALDÚA
Leartiker
PETER BOVENDEERD
Technische Universiteit
Eindhoven
STEFAN JANSSENS
Katholieke Universiteit Leuven
PAULA ALVES
Instituto de Biologia
Experimental e Tecnologica
JEANETT BOLTHER
PNO Innovation
Innovation & Exploitation Committee
FELIPE PROSPER
Universidad de Navarra
STEFAN JANSSENS
Katholieke Universiteit Leuven
JÜRGEN GROLL
University Hospital Würzburg
PAULA ALVES
Instituto de Biologia
Experimental e Tecnologica
NURIA MONSERRAT
Fundacio Institut de Bioenginyeria
de Catalunya
PETER BOVENDEERD
Technische Universiteit
Eindhoven
JEANETT BOLTHER
PNO Innovation
ANA ESPERT
PNO Innovation
AIDEN FLANAGAN
Boston Scientific
JOHANNES PAULIDES
AE Medicalis
OSCAR GONZÁLEZ
Universidad de Navarra
External Advisory Board
PHILIPPE MENASCHÉ
Hôpital Européen Georges-Pompidou
ELENA DE JUAN
The University of Western Australia
MAXIME SERMESANT
Université Côte D’Azur
CARLIJN BOUTEN
Technische Universiteit Eindhoven
ANA ARANDA
Servicio Murciano de Salud
ANTONIO PARDO
Universidad de Navarra
TOMAS FAJARDO
CardioAlianza